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Bioactivity:
MI-773 (SAR405838) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.
CAS nr:
1303607-60-4
Purity:
98%
Molecular Weight:
562,5
SMILES:
CC(C)(C)C[C@@H]1N[C@H]([C@H](c2cccc(Cl)c2F)[C@]11C(=O)Nc2cc(Cl)ccc12)C(=O)N[C@H]1CC[C@H](O)CC1
Formula:
C29H34Cl2FN3O3
Pathway:
Apoptosis,Ubiquitination
Target:
Mdm2,E1/E2/E3 Enzyme