Bioactivity:

E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling. E6446 works in a variety of human and mouse cell types and inhibits DNA-TLR9 interaction in vitro. When administered to mice, this compound suppress responses to challenge doses of cytidine-phospha

CAS nr:

1219925-73-1

Purity:

98%

Molecular Weight:

449,6

SMILES:

C1CCN(C1)CCCOc1ccc(cc1)c1nc2c(o1)cc(cc2)OCCCN1CCCC1

Formula:

C27H35N3O3

Pathway:

Immunology/Inflammation

Target:

TLR