Bioactivity:

Necrostatin-34 is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a distinct binding pocket in the kinase domain.

CAS nr:

375835-43-1

Purity:

98%

Molecular Weight:

384,48

SMILES:

O=C(NC1=NC=CS1)CSC2=C(C#N)C(C3=CC=C(C)C=C3)CC(N2)=O

Formula:

C18H16N4O2S2

Pathway:

NF-_b,Apoptosis

Target:

RIP kinase,RIP kinase