Bioactivity:

A-770041 is selective and orally active Src-family Lck inhibitor, and the other Src family kinase involved in T-cell signaling. A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, IC50 value: 147 nM Target: Lck.

CAS nr:

869748-10-7

Purity:

98%

Molecular Weight:

621,73

SMILES:

CC(N(CC1)CCN1C(CC1)CCC1n(c1ncnc(N)c11)nc1-c(cc1)cc(OC)c1NC(c1cc(cccc2)c2n1C)=O)=O

Formula:

C34H39N9O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

Src,Src