Bioactivity:

EF24 treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.

CAS nr:

342808-40-6

Purity:

98%

Molecular Weight:

347,79

SMILES:

O=C1/C(CNC/C1=C\C2=C(F)C=CC=C2)=C/C3=C(F)C=CC=C3.[H]Cl

Formula:

C19H16ClF2NO

Pathway:

Proteases/Proteasome,Apoptosis,MAPK,MAPK

Target:

Caspase,Caspase,MEK,ERK