Bioactivity:

CBS9106 (SL-801) is a reversible oral inhibitor of CRM1 with CRM1 degrading and antitumor activities. CBS9106 arrests the cell cycle and inducing apoptosis in a time- and dose-dependent manner for a broad spectrum of cancer cells.

CAS nr:

1076235-04-5

Purity:

98%

Molecular Weight:

419,83

SMILES:

O=C(C(COCCC(C)(C)C)=C1C)N(NC2=NC(Cl)=C(C(F)(F)F)C=C2)C1=O

Formula:

C18H21ClF3N3O3

Pathway:

Membrane transporter/Ion channel

Target:

CRM1