Bioactivity:

20(S)-hydroxyCholesterol is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog signaling pathway with an EC50 of 3 _M in NIH3T3 cells.

CAS nr:

516-72-3

Purity:

98%

Molecular Weight:

402,65

SMILES:

C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1

Formula:

C27H46O2

Pathway:

Others

Target:

Others