Bioactivity:

BMS CCR2 22 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) antagonist. It has excellent binding affinity (binding IC50 of 5.1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM)[1][2].

CAS nr:

445479-97-0

Purity:

98%

Molecular Weight:

593,66

SMILES:

O=C(NCC(N[C@@H]1[C@H](NC(C2=CC=C(SC)C=C2)=O)CCCC1)=O)C3=CC(C(F)(F)F)=CC=C3NC(NC(C)C)=O

Formula:

C28H34F3N5O4S

Pathway:

Microbiology/Virology,Immunology/Inflammation

Target:

CCR,CCR