Bioactivity:

Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B.�Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad rang

CAS nr:

87081-36-5

Purity:

98%

Molecular Weight:

526,7

SMILES:

O=C(O)/C=C(C)/C[C@H](C)[C@@H](O)[C@H](C)C([C@H](C)/C=C(C)/C=C/C[C@@H](C)/C=C(C)\C=C\[C@H]1[C@@H](C)C=CC(O1)=O)=O

Formula:

C32H46O6

Pathway:

Membrane transporter/Ion channel

Target:

CRM1