Bioactivity:

Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38_ and p38_ enzymatic activity with IC50 values of 0.014ﾱ0.002 and 0.48ﾱ 0.04 microM, respectively with no activity against p38delta or p3

CAS nr:

449811-01-2

Purity:

98%

Molecular Weight:

406,38

SMILES:

Cn1c2nc(ncc2cc(c1=O)Oc1c(cc(cc1)F)F)NC(CCO)CCO

Formula:

C19H20F2N4O4

Pathway:

Autophagy,MAPK

Target:

Autophagy,p38 MAPK