Bioactivity:

GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor ( IC50: 8.6 nM for binding RIP3 kinase domain; IC50: 6.5 nM for inhibiting kinase activity).

CAS nr:

1601496-05-2

Purity:

98%

Molecular Weight:

377,49

SMILES:

NC1=NC=C(C2=CC(C)=NN2C)C3=C1C(C4=CC=C(SC=N5)C5=C4)=CS3

Formula:

C19H15N5S2

Pathway:

Apoptosis

Target:

TNF