Bioactivity:

CS-2660, a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM.

CAS nr:

951151-97-6

Purity:

98%

Molecular Weight:

364,79

SMILES:

CCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC(=C2/C=N/OC)N)Cl

Formula:

C15H17ClN6O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Apoptosis,Tyrosine Kinase/Adaptors

Target:

VEGFR,VEGFR,c-RET,c-RET,c-Kit