dBET6 T5130
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.
CAS nr:
1950634-92-0
Purity:
98%
Molecular Weight:
841,37
SMILES:
Cc1sc-2c(c1C)C(=N[C@@H](CC(=O)NCCCCCCCCNC(=O)COc1cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c13)c1nnc(C)n-21)c1ccc(Cl)cc1
Formula:
C42H45ClN8O7S
Pathway:
Chromatin/Epigenetic,Apoptosis
Target:
Epigenetic Reader Domain,Apoptosis
