Uprosertib T6849
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
CAS nr:
1047634-65-0
Purity:
98%
Molecular Weight:
429,25
SMILES:
Cn1c(c(cn1)Cl)c1c(oc(c1)C(=O)N[C@@H](Cc1cc(c(cc1)F)F)CN)Cl
Formula:
C18H16Cl2F2N4O2
Pathway:
Cytoskeletal Signaling,PI3K/Akt/mTOR signaling
Target:
Akt,Akt