Bioactivity:

Dot1L-IN-5 is a potent disruptor of telomeric silencing 1-like protein (DOT1L) inhibitor with an IC50 SPA DOT1L of 0.17 nM.

CAS nr:

T11084

Purity:

98%

Molecular Weight:

592,96

SMILES:

O=S(C1=CC=C(N[C@H](C2=NC=CC=C2Cl)C3=C4OC(F)(F)OC4=CC=C3)C(NC5=NC(N)=NC(OC)=N5)=C1)(N)=O

Formula:

C23H19ClF2N8O5S

Pathway:

Chromatin/Epigenetic

Target:

Histone Methyltransferase