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Bioactivity:
JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.
CAS nr:
1334673-53-8
Purity:
98%
Molecular Weight:
380,44
SMILES:
O=C(C1=CNC2=NC=C(C3CC3)N=C21)N[C@@H](C(N4CC(C#N)C4)=O)C(C)(C)C
Formula:
C20H24N6O2
Pathway:
Others
Target:
Others