TargetMol Chemicals

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PD173074 T2642

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src.

CAS nr:

219580-11-7

Purity:

98%

Molecular Weight:

523,67

SMILES:

CCN(CC)CCCCNc1ncc2cc(-c3cc(OC)cc(OC)c3)c(NC(=O)NC(C)(C)C)nc2n1

Formula:

C28H41N7O3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling,Apoptosis

Target:

IGF-1R,VEGFR,VEGFR,Src,Src,FGFR,FGFR,EGFR,EGFR,EGFR,Apoptosis