Bioactivity:

IAXO-102 is a TLR4 antagonist that negatively regulates TLR4 signaling. It inhibits MAPK and p65 NF-_B phosphorylation and expression of TLR4 dependent proinflammatory protein. IAXO-102 also prevents experimental abdominal aortic aneurysm development.

CAS nr:

1115270-63-7

Purity:

98%

Molecular Weight:

585,94

SMILES:

CCCCCCCCCCCCCCO[C@@H]([C@@H]([C@@H](CN)O[C@@H]1OC)O)[C@H]1OCCCCCCCCCCCCCC

Formula:

C35H71NO5

Pathway:

Immunology/Inflammation

Target:

TLR