Bioactivity:

OSI-930, an orally active inhibitor of c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2), targets cancer cell proliferation and blood vessel growth (angiogenesis) in tumors.

CAS nr:

728033-96-3

Purity:

98%

Molecular Weight:

443,44

SMILES:

FC(F)(F)OC1=CC=C(NC(=O)C2=C(NCC3=CC=NC4=CC=CC=C34)C=CS2)C=C1

Formula:

C22H16F3N3O2S

Pathway:

MAPK,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Apoptosis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors

Target:

Raf,FLT,FLT,VEGFR,VEGFR,CSF-1R,Src,Src,Apoptosis,c-Fms,c-Kit