Bioactivity:

Nocodazole is a synthetic inhibitor of microtubule polymerization, also inhibits Abl (IC50: 0.21 _M), Abl(E255K, IC50: 0.53 _M) and Abl(T315I, IC50: 0.64 _M) in cell-free assays. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassemb

CAS nr:

31430-18-9

Purity:

98%

Molecular Weight:

301,32

SMILES:

COC(=O)Nc1nc2c([nH]1)cc(cc2)C(=O)c1cccs1

Formula:

C14H11N3O3S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Cytoskeletal Signaling,DNA Damage/DNA Repair,Autophagy,Apoptosis

Target:

Bcr-Abl,Bcr-Abl,Bcr-Abl,Microtubule Associated,CRISPR/Cas9,Autophagy,Apoptosis