ML216 T5413
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
ML-216 is a small molecule inhibitor of BLM helicase (IC50: 1.8 _M). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 _M).
CAS nr:
1430213-30-1
Purity:
98%
Molecular Weight:
383,32
SMILES:
Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Formula:
C15H9F4N5OS
Pathway:
DNA Damage/DNA Repair,Cell Cycle/Checkpoint
Target:
DNA/RNA Synthesis,DNA/RNA Synthesis
