Bioactivity:

BPH-1358 (NSC50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 _M and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].

CAS nr:

5352-53-4

Purity:

98%

Molecular Weight:

601,53

SMILES:

O=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5.[H]Cl.[H]Cl

Formula:

C32H30Cl2N6O2

Pathway:

Microbiology/Virology,Others

Target:

Antibacterial,Others