Bioactivity:

GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of pan-Pim kinase (Kis: 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively).

CAS nr:

1428569-85-0

Purity:

98%

Molecular Weight:

465,5

SMILES:

FC1=CC=CC(F)=C1C2=NC(C(NC3=C(N4CC[C@@H](F)[C@H](N)CC4)N(C)N=C3)=O)=C(N)S2

Formula:

C20H22F3N7OS

Pathway:

JAK/STAT signaling,Chromatin/Epigenetic

Target:

Pim,Pim