Bioactivity:

(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-_-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter recep

CAS nr:

195881-94-8

Purity:

98%

Molecular Weight:

331,81

SMILES:

Cl.NCC1=CNC(=S)N1[C@@H]1CCC2=C(F)C=C(F)C=C2C1

Formula:

C14H15F2N3S�HCl

Pathway:

Metabolism

Target:

Hydroxylase