Bioactivity:

Plinabulin (NPI-2358) is a vascular disrupting agent (VDA) against tubulin-depolymerizing tumor cells ( IC50: 9.8-18 nM). Plinabulin selectively targets and binds to the colchicine-binding site of tubulin, thereby interrupting equilibrium of microtubule d

CAS nr:

714272-27-2

Purity:

98%

Molecular Weight:

336,39

SMILES:

CC(C)(C)c1c(nc[nH]1)/C=c\1/c(=O)[nH]/c(=C\c2ccccc2)/c(=O)[nH]1

Formula:

C19H20N4O2

Pathway:

Cytoskeletal Signaling

Target:

Microtubule Associated