Bioactivity:

BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 _M) and is active against S. aureus in vitro (MIC ~250 ng/mL).

CAS nr:

801985-13-7

Purity:

98%

Molecular Weight:

528,6

SMILES:

O=C(C1=CC=C(C2=CC=C(C(NC3=CC=CC(C4=NCCN4)=C3)=O)C=C2)C=C1)NC5=CC=CC(C6=NCCN6)=C5

Formula:

C32H28N6O2

Pathway:

Others

Target:

Others