TargetMol Chemicals

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(ﾱ)-AMG 487 T22477

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively).

CAS nr:

T22477

Purity:

98%

Molecular Weight:

603,59

SMILES:

CCOC1=CC=C(N2C(C(N(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC4=CN=CC=C4)C)=NC5=C(C2=O)C=CC=N5)C=C1

Formula:

C32H28F3N5O4

Pathway:

Others

Target:

Others