Bioactivity:

GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC50 values of 3 and >�20 _M in vivo, respectiv

CAS nr:

180977-44-0

Purity:

98%

Molecular Weight:

479,63

SMILES:

CC(C)C[C@@H](C(OC)=O)NC(C1=CC=C(NC[C@@H](N)CS)C=C1C2=C3C=CC=CC3=CC=C2)=O

Formula:

C27H33N3O3S

Pathway:

Others

Target:

Others