Bioactivity:

LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43ﾱ0.36 _M. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99ﾱ3.23 _M. LX2343 stimulates autophagy in its promotion of A_ clearance.

CAS nr:

333745-53-2

Purity:

98%

Molecular Weight:

474,91

SMILES:

Clc1cc(c(OC)cc1)N(CC(=O)Nc2ccc3OCOc3c2)S(=O)(=O)c4ccccc4

Formula:

C22H19ClN2O6S

Pathway:

Neuroscience,PI3K/Akt/mTOR signaling,Neuroscience,Autophagy,Neuroscience

Target:

Beta Amyloid,PI3K,Beta-Secretase,Autophagy,BACE