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Bioactivity:
PLX-4720 is a potent and selective inhibitor of B-Raf (V600E) (IC50: 13 nM), equally potent to c-Raf-1(Y340D and Y341D mutations).
CAS nr:
918505-84-7
Purity:
98%
Molecular Weight:
413,83
SMILES:
CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F
Formula:
C17H14ClF2N3O3S
Pathway:
MAPK
Target:
Raf