Bioactivity:

LX7101 is an effective inhibitor of LIMK and ROCK2 (IC50: 24, 1.6, and 10 nM for LIMK1, LIMK2, and ROCK2, respectively). It also inhibits PKA (IC50 <1 nM).

CAS nr:

1192189-69-7

Purity:

98%

Molecular Weight:

451,52

SMILES:

O=C(OC1=CC=CC(NC(C2(CN)CCN(C3=C4C(NC=C4C)=NC=N3)CC2)=O)=C1)N(C)C

Formula:

C23H29N7O3

Pathway:

Tyrosine Kinase/Adaptors,Cell Cycle/Checkpoint,Cytoskeletal Signaling,Cell Cycle/Checkpoint,Stem Cells

Target:

PKA,LIM Kinase,ROCK,ROCK,ROCK