TargetMol Chemicals

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AMG 517 T6379

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.

CAS nr:

659730-32-2

Purity:

98%

Molecular Weight:

430,4

SMILES:

CC(=O)Nc1nc2c(cccc2s1)Oc1ncnc(c1)c1ccc(cc1)C(F)(F)F

Formula:

C20H13F3N4O2S

Pathway:

Membrane transporter/Ion channel

Target:

TRP/TRPV Channel