Nutlin-3b T6614
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Nutlin-3b is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 _M), 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
CAS nr:
675576-97-3
Purity:
98%
Molecular Weight:
581,49
SMILES:
CC(C)Oc1c(ccc(c1)OC)C1=N[C@@H]([C@@H](N1C(=O)N1CCNC(=O)C1)c1ccc(cc1)Cl)c1ccc(cc1)Cl
Formula:
C30H30Cl2N4O4
Pathway:
Apoptosis,Ubiquitination
Target:
Mdm2,E1/E2/E3 Enzyme
