Bioactivity:

Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM). Fenobam has anxiolytic activity. Fenobam is a selective and non-competitive mGluR5 antagonist acting at an allosteric modulatory site (Kd values are 54 and

CAS nr:

57653-26-6

Purity:

98%

Molecular Weight:

266,68

SMILES:

O=C(NC1=NC(CN1C)=O)NC2=CC=CC(Cl)=C2

Formula:

C11H11ClN4O2

Pathway:

Neuroscience

Target:

GluR