J-113863 T11699
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
J-113863 is also a potent antagonist of the human CCR3 (IC50 of 0.58 nM) , but a weak antagonist of the mouse CCR3 (IC50 of 460 nM). J-113863 is inactive against CCR2, CCR4 and CCR5, as well as the LTB4 or TNF-_ receptors. Anti-inflammatory effect. J-1138
CAS nr:
353791-85-2
Purity:
98%
Molecular Weight:
655,44
SMILES:
[I-].CC[N+]1(C\C2=C\CCCCCC2)CCC(CC1)NC(=O)C1c2cc(Cl)ccc2Oc2ccc(Cl)cc12
Formula:
C30H37Cl2IN2O2
Pathway:
Microbiology/Virology,Immunology/Inflammation
Target:
CCR,CCR
