Bioactivity:

PAT-048 is an effective and selective autotaxin inhibitor. PAT-048 reduces dermal fibrosis in vivo. PAT-048 also inhibits IL-6 mRNA expression but displays no effect on autotaxin protein and pulmonary lysophosphatidic acid (LPA) production in the lung fib

CAS nr:

1359983-15-5

Purity:

98%

Molecular Weight:

461,91

SMILES:

CCCN1N=CC(N2C3=C(C(SC4=CC=CC(C(O)=O)=C4F)=C2C)C=CC(Cl)=C3F)=C1

Formula:

C22H18ClF2N3O2S

Pathway:

Metabolism

Target:

PDE