Bioactivity:

FzM1.8 is an FZD4 allosteric agonist (pEC50: 6.4. FzM1.8). It binds to FZD4 and activates the WNT/_-catenin pathway, by promoting TCF/LEF transcriptional activity in the absence of any WNT ligand. It also stimulates the release of the G__ subunit that in

CAS nr:

2204290-85-5

Purity:

98%

Molecular Weight:

322,31

SMILES:

O=C(O)C1=CC(NC(NC2=CC=C3C=CC=CC3=C2)=O)=CC(O)=C1

Formula:

C18H14N2O4

Pathway:

Others

Target:

Others