Bioactivity:

Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).

CAS nr:

145317-11-9

Purity:

98%

Molecular Weight:

460,96

SMILES:

O=C(C(C1=C(CC(CN)CC2)N2C3=C1C=CC=C3)=C4C5=CN(C)C6=C5C=CC=C6)NC4=O.[H]Cl

Formula:

C26H25ClN4O2

Pathway:

Chromatin/Epigenetic,Cell Cycle/Checkpoint,Cytoskeletal Signaling

Target:

PKC,CDK,PKC