Bioactivity:

GSK172981 is a non-peptide tachykinin NK3 receptor antagonist with a high affinity for the recombinant human (PK (I) value 7.7) and native guinea pig (PK (I) value 7.8) tachykinin NK3 receptor. In vitro, the functional evaluation showed that GSK172981 was

CAS nr:

1133705-99-3

Purity:

98%

Molecular Weight:

411,48

SMILES:

O=C(C1=C(N)C(C2=CC=CC(F)=C2)=NC3=CC=CC=C13)N[C@@H](C4CC4)C5=CC=CC=C5

Formula:

C26H22FN3O

Pathway:

Target: