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Bioactivity:
PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
CAS nr:
717906-29-1
Purity:
98%
Molecular Weight:
506,5
SMILES:
n1c(nc(c(c1)C(F)(F)F)NCc1c(cccc1)N(C)S(=O)(=O)C)Nc1ccc2c(c1)CC(=O)N2
Formula:
C22H21F3N6O3S
Pathway:
Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Tyrosine Kinase/Adaptors
Target:
FAK,FAK,FAK,PYK2