Bioactivity:

PF-06737007 is an effective inhibitor of pan-Trk in cell-based assays (IC50s: 7.7 nM, 15 nM, and 3.9 nM for TrkA, TrkB, and TrkC, respectively).

CAS nr:

1863905-38-7

Purity:

98%

Molecular Weight:

528,49

SMILES:

O=C(N)C1=CC=C(OCC(C)(O)C)C=C1O[C@@H]2[C@H](F)CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC2

Formula:

C25H28F4N2O6

Pathway:

Tyrosine Kinase/Adaptors

Target:

Trk receptor