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Bioactivity:
JG26 is an ADAM17 inhibitor. JG26 inhibits AngII-induced EGFR transactivation and ERK activation in vascular smooth muscle cells (VSMCs).
CAS nr:
1464910-32-4
Purity:
98%
Molecular Weight:
594,28
SMILES:
O=C(NO)[C@H](NS(=O)(C1=CC=C(OCC2=CC(Br)=CC(Br)=C2)C=C1)=O)CCCNC(N)=O
Formula:
C19H22Br2N4O6S
Pathway:
Target: