Bioactivity:

ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation.�ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 _M) activity.

CAS nr:

301177-43-5

Purity:

98%

Molecular Weight:

353,48

SMILES:

N#CC1=C(C2CCCCC2)N=C(SCC3=CC(C)=CC=C3C)NC1=O

Formula:

C20H23N3OS

Pathway:

GPCR/G Protein

Target:

cAMP