Bioactivity:

MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 _M). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42.

CAS nr:

10179-57-4

Purity:

98%

Molecular Weight:

377,46

SMILES:

C1C(N(N=C1C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4

Formula:

C21H19N3O2S

Pathway:

MAPK,GPCR/G Protein,Cell Cycle/Checkpoint

Target:

Ras,Ras,CDK