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Bioactivity:
Talazoparib is a new-type PARP inhibitor (IC50: 0.58 nM), It similarly binds to PARP1/2 (Kis: 1.2/0.85 nM).
CAS nr:
1207456-01-6
Purity:
98%
Molecular Weight:
380,35
SMILES:
Cn1ncnc1[C@@H]1[C@H](N=c2cc(F)cc3C(=O)NNC1=c23)c1ccc(F)cc1
Formula:
C19H14F2N6O
Pathway:
DNA Damage/DNA Repair,Chromatin/Epigenetic
Target:
PARP,PARP