Bioactivity:

DLK-IN-1 is a selective oral active inhibitor of bisleucine zipper kinase (DLK, MAP3K12) with Ki of 3 nM. DLK-IN-1 is active in the Alzheimer's disease model, retains excellent CNS permeability, and after multiple days of administration, its concentration

CAS nr:

1620574-24-4

Purity:

98%

Molecular Weight:

423,43

SMILES:

CC(N1C([C@@H]2[C@]3([H])[C@@]2([H])CN(C4COC4)C3)=CC(C5=CN=C(N)C(OC(F)(F)F)=C5)=N1)C

Formula:

C20H24F3N5O2

Pathway:

DNA Damage/DNA Repair

Target:

DNA Alkylation