Bioactivity:

RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 _M, 4.0 _M, and 4.1 _M for hTRPV4, mTRPV4, and rTRPV4 respectively). RN-1747 also antagonizes TRPM8 (IC50: 4 _M).

CAS nr:

1024448-59-6

Purity:

98%

Molecular Weight:

395,86

SMILES:

O=S(N1CCN(CC2=CC=CC=C2)CC1)(C3=CC=C(Cl)C=C3[N+]([O-])=O)=O

Formula:

C17H18ClN3O4S

Pathway:

Membrane transporter/Ion channel

Target:

TRP/TRPV Channel