Bioactivity:

Pemetrexed is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed therapy has been associated with moderate rates of serum enzyme elevations dur

CAS nr:

150399-23-8

Purity:

98%

Molecular Weight:

471,37

SMILES:

[Na+].[Na+].Nc1nc2[nH]cc(CCc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)c2c(=O)[nH]1

Formula:

C20H19N5Na2O6

Pathway:

DNA Damage/DNA Repair,Metabolism,Cell Cycle/Checkpoint,Cell Cycle/Checkpoint,Autophagy,Apoptosis,Cell Cycle/Checkpoint,DNA Damage/DNA Repair

Target:

DHFR,DHFR,DHFR,Antifolate,Autophagy,Apoptosis,DNA/RNA Synthesis,DNA/RNA Synthesis