Uzansertib phosphate T12477
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
INCB053914 phosphate is an orally active, ATP-competitive inhibitor of pan-PIM kinase(PIM1, PIM2, PIM3 with IC50s of 0.24 nM, 30 nM, 0.12 nM , respectively).
CAS nr:
2088852-47-3
Purity:
98%
Molecular Weight:
611,51
SMILES:
O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.O=P(O)(O)O
Formula:
C26H29F3N5O7P
Pathway:
JAK/STAT signaling,Chromatin/Epigenetic
Target:
Pim,Pim