TargetMol Chemicals

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BRD6989 T14778

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

BRD6989 is an analog of the natural product cortistatin A (dCA). Which inhibits CDK8 and upregulates IL-10. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM.

CAS nr:

642008-81-9

Purity:

98%

Molecular Weight:

264,33

SMILES:

CC1CCc2nc(N)c(C#N)c(-c3cccnc3)c2C1

Formula:

C16H16N4

Pathway:

Immunology/Inflammation,Immunology/Inflammation,Cell Cycle/Checkpoint

Target:

IL Receptor,Interleukin,CDK